סמינר מחלקתי 2.11.15

School of Mechanical Engineering Seminar
Monday, November 2, 2015 at 15:00
Wolfson Building of Mechanical Engineering, Room 206

Arterial stiffening in pulmonary hypertension: measurement, cause and effect

Prof. Naomi Chesler

Department of Biomedical Engineering

University of Wisconsin – Madison

Pulmonary arterial hypertension (PAH) is a rare and rapidly fatal disease.  Severity is typically assessed via pressure elevation due to distal arterial narrowing but proximal arterial stiffening is a better predictor of mortality.  Multiple approaches are available to measure pulmonary artery stiffening, including in vivo and ex vivo techniques.  In this talk, state of the art approaches to measuring arterial stiffening in PAH will be presented, as well as causes and consequences of arterial stiffening for pulmonary hemodynamics, right ventricular function and the quality of life for patients with PAH.