סמינר המחלקה להנדסה ביו רפואית

In vivo microscopy of blood

Prof. Dvir Yelin

Faculty of Biomedical Engineering, Technion, Israel

In vivo microscopy of blood

Measuring the composition of a patient blood is often the first step in clinical diagnosis, and is most commonly performed by extracting a blood sample for laboratory analysis that provides invaluable information on patient condition. The use of invasive blood extraction, however, is often problematic with chronic patients, infants, and patients with needle phobia. Moreover, in areas with poor accessibility to large healthcare facilities and poor sanitary conditions, blood tests become challenging due to high risk of infection, sample contamination, and long waits for the test results. Several technologies exist for measuring single blood parameters (oxygen saturation, hemoglobin etc.) without using needles; however, these techniques suffer from low accuracy, high sensitivity to skin color, and provide very few parameters that are often insufficient for diagnosis. A novel optical encoding technology, recently developed by our research group, allows high-resolution confocal microscopy of individual blood cells flowing within small blood vessels in the oral mucosa. The technique uses encoded imaging that allows real-time microscopy of a single transverse line within a blood vessel, producing detailed images of the passing blood cells, which are then analyzed for measuring the blood content and cell morphology. Based on the subcellular-resolution image data, the system can study blood cell flow within the body and potentially provide blood testing noninvasively at the point of care.

ההרצאה תתקיים ביום ראשון 20.11.16, בשעה 15:00

בחדר 315, הבניין הרב תחומי, אוניברסיטת תל אביב