אסף ליברמן

תלמיד התואר השלישי במחלקה להנדסה ביו רפואית

אוניברסיטת תל אביב

Cell Studio: a platform for real-time, interactive 3D Graphical simulation of immunological processes

In the core of systems biology are computer models, which integrate static experimental ‘omics’ data into dynamic representations of the researched biological system. These representations are then simulated - run on a computer – to promote understanding of the system. The field of computer modeling and simulation of biological systems is rapidly advancing, with many simulation systems created in the past 20 years. It is backed by significant progress in the fields of experimentation techniques, computer hardware and programming software. The result of a simulation may be delivered in several ways, from numerical results, through graphs of the simulated run, to a visualization of the simulation. The vision of an in-silico experiment viewed as if it was undertaken in reality under a microscope is appealing, but technically demanding and computationally-intensive. We use game engines - generic programs for game creation that offer ready-made assets and tools - to create a visualized, interactive simulation. We also utilize a scalable architecture that delegates the computational load into a scalable server. Together, these may aid in overcoming technical challenges.

Here we report “Cell Studio”, a generic, hybrid platform to simulate an immune microenvironment with biological and biophysical rules. The simulation may be visualized in interactive real-time 3D: The user may view the simulation, move the ‘camera’ around, stop, fast-forward and rewind it, and inject soluble molecules into the extracellular medium at any point in time. During simulation, graphs are created in real time for a broad view of system wide processes. The model is parametrized using a user-friendly Graphical User Interface (GUI). We believe that real-time, interactive 3D visualization may improve insight generated from the simulation, and encourage intuition about emergent behavior in the modelled biological system.

העבודה נעשתה בהנחיית ד"ר אורי נבו מהמחלקה להנדסה ביו-רפואית,  אוניברסיטת תל-אביב

ההרצאה תתקיים ביום ראשון 23.04.17, בשעה 14:30

בחדר 315, הבניין הרב תחומי, אוניברסיטת תל אביב

Speaker: Shani Gat

M.Sc. student under the supervision of Prof. Hagit Messer-Yaron

Sunday, April 23^rd, 2017 at 15:30

Room 011, Kitot Bldg., Faculty of Engineering

Robust Estimation and Mapping of Rainfall from Microwave Measurements

Estimation of a tempo-spatial field for purposes of environmental monitoring is often based on a network of local sensors, which are prone to measurement errors. As sensor networks become larger and cheaper, the probability of faulty sensors and measurements outliers rises. Moreover, the recently proposed approach of opportunistic sensors network, as in the case where commercial microwave links (CMLs) are used as rainfall sensors, also introduces a new source of errors. In this work, I refer to different approaches and methods for spatial interpolation from point measurements, with an emphasis on the problem of estimating data from microwave links, and suggested an iterative estimator based on Maximum Likelihood (ML) approach to the problem. I propose to increase the robustness of this approach based on the Huber’s M-Estimation method, and suggested a robust variation to the proposed algorithm accordingly: an algorithm based on the Huber loss function, and another censoring algorithm. The algorithms’ robustness was initially tested numerically. This test has shown that each robust variation had an advantage in different situations. The suggested algorithms were tested for several simulated scenarios, where a robust version showed a considerable advantage in the presence of outliers, versus the ML version and the AIDW reference algorithms. Finally, the algorithms were applied for actual CMLs’ real data, provided by Ericsson for the Gothenburg area. The results of the robust algorithms were not significantly different from the non-robust, suggesting that outliers may not be a major source of errors in this case.

סיור במרכז המבקרים של קו הרכבת המהירה לירושלים 

 בואו לבקר בפרויקט התשתיות הגדול בישראל
הקו המהיר של הרכבת ירושלים- תל אביב

 הסיור יתקיים ביום שלישי 25.04.17

מספר המקומות מוגבל

ההשתתפות בתשלום סמלי 

 יש להירשם ולשלם מראש על מנת להבטיח מקומך 

 לתשלום בסך 25 ש"ח הקליקו כאן

מדריך הישרדות לחיים שאחרי האקזיט 
ד"ר גיל ברוש 
בוגר הפקולטה, מגמה להנדסת תעשייה

בואו לשמוע מה קורה לסטארט-אפ לאורך השנים שלאחר הרכישה?
האם החלום מתגשם?
האם במבט לאחור אפשר היה לעשות זאת טוב יותר?

לפרטים והרשמה לחץ כאן
התמונה לקוחה מדה מרקר  09.03.12